- Countries/Regions
- United States of America
- Category
- Research
- Academic Field
- Medicine
- Related goals of SDGs
| Keyword |
Neuroscience, Glia, oligodendrocyte, myelin, proteomics |
Information on Niigata University
| Name of the professor/researcher |
(1) TAKEBAYASHI Hirohide (2) BIZEN Norihisa |
| Position/Faculty |
(1) Professor, Graduate School of Medical and Dental Sciences (2) Assistant Professor, Graduate School of Medical and Dental Sciences |
Information on the Counterpart
| Countries/Regions |
USA |
| Faculty/Institution |
UConn Health |
Detailed Information/Report on Activities
Oligodendrocytes (OLs) are myelin-forming glial cells in the central nervous system and are known to generate saltatory conduction and provide metabolic support for axonal health. In this study, we aim to comprehensively elucidate the dynamics of proteins, lipids, and glycans underlying OL and myelin abnormalities in spontaneously mutant and genetically engineered mice with OL abnormalities, in collaboration with Prof. Riqiang Yan (UConn Health) and his colleagues who possess myelin proteomics technology. In FY2022, Assistant Professor Norihisa Bizen visited Prof. Yan’s lab at UConn Health to learn how to extract myelin proteins with the support of an Accelerated International Research Grant.
